Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 2/20 | 0.32 |
| ▸ | HINT1 | P49773 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505749 | 0.90 | TYMP (0.48) | TYMPKDM4ECYP1A2TAS1R3TAS1R1 | |
| SCHEMBL13493900 | 0.88 | TYMP (0.48) | TYMPKDM4ECYP1A2TAS1R3TAS1R1 | |
| SCHEMBL21473339 | 0.88 | TYMP (0.48) | TYMPKDM4ECYP1A2TAS1R3TAS1R1 | |
| SCHEMBL19505895 | 0.87 | TYMP (0.49) | TYMPKDM4ECYP1A2TAS1R3TAS1R1 | |
| SCHEMBL15488821 | 0.82 | TYMP (0.45) | TYMPKDM4ECYP1A2TAS1R3TAS1R1 | |
| SCHEMBL15489089 | 0.81 | TYMP (0.53) | TYMPCYP1A2HPGDTAAR1ALDH1A1 | |
| SCHEMBL1697170 | 0.81 | TYMP (0.43) | TYMPKDM4ECYP1A2TAS1R3TAS1R1 | |
| SCHEMBL15488822 | 0.80 | TYMP (0.43) | TYMPKDM4ECYP1A2TAS1R3TAS1R1 | |
| SCHEMBL16451656 | 0.80 | TYMP (0.43) | TYMPKDM4ECYP1A2TAS1R3TAS1R1 | |
| SCHEMBL16451657 | 0.80 | TYMP (0.43) | TYMPKDM4ECYP1A2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732112-B2 | Synthesis of 2′,3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2017-08-15 | — | — | US | disclosed |