Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 4/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13493900 | 1.00 | TYMP (0.48) | TYMPKDM4ETAS1R3TAS1R1CYP1A2 | |
| SCHEMBL19505895 | 0.92 | TYMP (0.49) | TYMPKDM4ETAS1R3TAS1R1CYP1A2 | |
| SCHEMBL31093208 | 0.91 | TYMP (0.51) | TYMPKDM4ETAS1R3TAS1R1HPGD | |
| SCHEMBL19505749 | 0.91 | TYMP (0.48) | TYMPKDM4ETAS1R3TAS1R1CYP1A2 | |
| SCHEMBL21065504 | 0.88 | TYMP (0.47) | TYMPKDM4ETAS1R3TAS1R1LMNA | |
| SCHEMBL22034235 | 0.88 | TYMP (0.52) | TYMPKDM4ETAS1R3TAS1R1HPGD | |
| SCHEMBL21878091 | 0.88 | TYMP (0.52) | TYMPKDM4ETAS1R3TAS1R1HPGD | |
| SCHEMBL18490587 | 0.88 | TYMP (0.47) | TYMPKDM4ETAS1R3TAS1R1LMNA | |
| SCHEMBL18490457 | 0.88 | TYMP (0.47) | TYMPKDM4ETAS1R3TAS1R1LMNA | |
| SCHEMBL19254058 | 0.88 | TYMP (0.43) | TYMPKDM4ETAS1R3TAS1R1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250368-A2 | ATXN2 RNA INTERFERENCE AGENTS | ELI LILLY AND COMPANY (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023177972-A1 | SARM1 RNA INTERFERENCE AGENTS | ELI LILLY AND COMPANY (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2023114700-A1 | MAPT RNA INTERFERENCE AGENTS | ELI LILLY AND COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |
| EP-3865576-A1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | Dicerna Pharmaceuticals, Inc. (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3569711-B1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | DICERNA PHARMACEUTICALS INC (US) | 2021-02-03 | — | — | EP | disclosed |
| EP-3569711-A1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | Dicerna Pharmaceuticals, Inc. (US) | 2019-11-20 | — | — | EP | disclosed |
| WO-2019200273-A1 | NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-10-17 | — | — | WO | disclosed |