Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 12/20 | 0.54 |
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400137 | 0.93 | CSNK2A1 (0.56) | CSNK2A1USP2TSHRNPSR1MAPT | |
| SCHEMBL19207420 | 0.89 | CSNK2A1 (0.61) | CSNK2A1USP2TSHRNPSR1MAPT | |
| SCHEMBL19254726 | 0.89 | CSNK2A1 (0.61) | CSNK2A1USP2TSHRNPSR1MAPT | |
| SCHEMBL19254356 | 0.88 | CSNK2A1 (0.59) | CSNK2A1USP2TSHRNPSR1MAPT | |
| SCHEMBL19254663 | 0.84 | MAPT (0.64) | CSNK2A1USP2TSHRNPSR1MAPT | |
| SCHEMBL19254664 | 0.83 | CSNK2A1 (0.52) | CSNK2A1USP2TSHRNPSR1MAPT | |
| SCHEMBL19254358 | 0.81 | CSNK2A1 (0.62) | CSNK2A1USP2TSHRNPSR1MAPT | |
| SCHEMBL19254727 | 0.81 | CSNK2A1 (0.65) | CSNK2A1USP2TSHRNPSR1MAPT | |
| SCHEMBL19254348 | 0.79 | CSNK2A1 (0.65) | CSNK2A1USP2TSHRNPSR1MAPT | |
| SCHEMBL19254351 | 0.79 | CSNK2A1 (0.74) | CSNK2A1USP2TSHRNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |