Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 12/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | USP2 | O75604 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19254726 | 0.92 | CSNK2A1 (0.61) | CSNK2A1KDM4EUSP2TSHRNPSR1 | |
| SCHEMBL19254358 | 0.91 | CSNK2A1 (0.62) | CSNK2A1KDM4EUSP2TSHRNPSR1 | |
| SCHEMBL19254305 | 0.90 | CSNK2A1 (0.70) | CSNK2A1KDM4EUSP2TSHRNPSR1 | |
| SCHEMBL22400137 | 0.88 | CSNK2A1 (0.56) | CSNK2A1KDM4EUSP2TSHRNPSR1 | |
| SCHEMBL19254805 | 0.87 | CSNK2A1 (0.85) | CSNK2A1KDM4EUSP2TSHRNPSR1 | |
| SCHEMBL19254594 | 0.87 | USP2 (0.68) | CSNK2A1KDM4EUSP2TSHRNPSR1 | |
| SCHEMBL22400146 | 0.86 | CSNK2A1 (0.55) | CSNK2A1KDM4EUSP2TSHRNPSR1 | |
| SCHEMBL19254652 | 0.86 | CSNK2A1 (0.55) | CSNK2A1KDM4EUSP2TSHRNPSR1 | |
| SCHEMBL19254356 | 0.85 | CSNK2A1 (0.59) | CSNK2A1KDM4EUSP2TSHRNPSR1 | |
| SCHEMBL19254292 | 0.85 | CSNK2A1 (0.67) | CSNK2A1KDM4EUSP2TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10765681-B2 | Purine compounds possessing anticancer activity | ACADEMIA SINICA (TW) | 2020-09-08 | — | — | US | disclosed |
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10765681-B2 | Purine compounds possessing anticancer activity | NTPCR, PNP, NUDT1 | CSNK2A1 2675/4885KDM4E 3979/4885USP2 4527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.