Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838740 | 0.91 | TSHR (0.59) | TSHRADRA2AADRA2BADRA2CCYSLTR2 | |
| SCHEMBL10979504 | 0.88 | TSHR (0.52) | TSHRADRA2AADRA2BADRA2CCYSLTR2 | |
| SCHEMBL20739985 | 0.84 | TSHR (0.52) | TSHRADRA2AADRA2BADRA2CCYSLTR2 | |
| SCHEMBL3844173 | 0.84 | TSHR (0.52) | TSHR | |
| SCHEMBL16583209 | 0.83 | TSHR (0.72) | TSHRADRA2AADRA2BADRA2CGABRA1 | |
| SCHEMBL4843352 | 0.83 | ADRA2A (0.46) | TSHRADRA2AADRA2BADRA2CCYSLTR2 | |
| SCHEMBL9621039 | 0.83 | ADRA2A (0.46) | TSHRADRA2AADRA2BADRA2CCYSLTR2 | |
| SCHEMBL3627333 | 0.83 | TSHR (0.59) | TSHRKDM4EL3MBTL1GABRA1GABRB2 | |
| SCHEMBL29429985 | 0.82 | TSHR (0.50) | TSHRHTR1AATM | |
| SCHEMBL5665152 | 0.82 | TSHR (0.50) | TSHRHTR1AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797878-B1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE | BIO-PHARM SOLUTIONS CO LTD (KR) | 2017-08-16 | — | — | EP | disclosed |