Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17683192 | 0.89 | EGFR (0.61) | EGFR | |
| SCHEMBL30460166 | 0.85 | EGFR (0.44) | EGFR | |
| SCHEMBL19540678 | 0.84 | EGFR (0.47) | EGFR | |
| SCHEMBL17683202 | 0.83 | EGFR (0.61) | EGFR | |
| SCHEMBL30459974 | 0.80 | EGFR (0.44) | EGFR | |
| SCHEMBL20869959 | 0.80 | EGFR (0.64) | EGFR | |
| SCHEMBL17682978 | 0.78 | EGFR (0.69) | EGFR | |
| SCHEMBL19540862 | 0.78 | EGFR (0.53) | EGFR | |
| SCHEMBL30459810 | 0.78 | EGFR (0.47) | EGFR | |
| SCHEMBL17683127 | 0.78 | EGFR (0.47) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205650-B1 | EGFR INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | SHANGHAI HANSOH BIOMEDICAL CO LTD (CN) | 2021-08-04 | — | — | EP | disclosed |
| EP-3205650-A1 | EGFR INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2017-08-16 | — | — | EP | disclosed |