Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436172 | 0.84 | AOC3 (0.42) | CYP1A2 | |
| SCHEMBL15078326 | 0.84 | CYP3A4 (0.33) | KDM4ELMNACYP1A2SMN1; SMN2KCNH2 | |
| SCHEMBL15078299 | 0.84 | CYP3A4 (0.33) | KDM4ELMNACYP1A2SMN1; SMN2KCNH2 | |
| SCHEMBL3435516 | 0.84 | AOC3 (0.42) | CYP1A2 | |
| SCHEMBL3435962 | 0.84 | AOC3 (0.42) | CYP1A2 | |
| SCHEMBL17446318 | 0.83 | ALDH1A1 (0.42) | ALDH1A1ESR1KDM4EPOLBNR3C2 | |
| SCHEMBL17446319 | 0.83 | ALDH1A1 (0.42) | ALDH1A1ESR1KDM4EPOLBNR3C2 | |
| SCHEMBL19384161 | 0.80 | KDM4E (0.48) | ALDH1A1KDM4EPOLBMAPTKMT2A | |
| SCHEMBL28636382 | 0.80 | KDM4E (0.48) | ALDH1A1KDM4EPOLBMAPTKMT2A | |
| SCHEMBL669484 | 0.80 | ALDH1A1 (0.44) | ALDH1A1ESR1KDM4EPOLBNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797878-B1 | PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE | BIO-PHARM SOLUTIONS CO LTD (KR) | 2017-08-16 | — | — | EP | disclosed |