⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209517 | 0.78 | — | — | |
| SCHEMBL11000228 | 0.74 | — | — | |
| SCHEMBL1359748 | 0.74 | — | — | |
| SCHEMBL11670290 | 0.74 | — | — | |
| SCHEMBL9431019 | 0.73 | ALDH1A1 (0.42) | — | |
| SCHEMBL11063751 | 0.72 | ALDH1A1 (0.40) | — | |
| SCHEMBL11068033 | 0.72 | ALDH1A1 (0.40) | — | |
| SCHEMBL14712444 | 0.72 | ALDH1A1 (0.40) | — | |
| SCHEMBL10969328 | 0.72 | — | — | |
| SCHEMBL11249511 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956188-B2 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-07 | — | — | US | disclosed |
| US-7772237-B2 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2010-08-10 | — | — | US | disclosed |
| EP-1817309-B1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-23 | — | — | EP | disclosed |
| US-20090105241-A1 | THIO-SUBSTITUTED TRICYCLIC AND BICYCLIC AROMATIC METHANESULFINYL DERIVATIVES | CEPHALON FRANCE (FR) | 2009-04-23 | — | — | US | disclosed |
| EP-1285908-B9 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-22 | — | — | EP | disclosed |
| US-7476690-B2 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2009-01-13 | — | — | US | disclosed |
| EP-1285908-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-20080171767-A1 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-17 | — | — | US | disclosed |
| EP-1817309-A1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | Syngeta Participations AG (CH) | 2007-08-15 | — | — | EP | disclosed |
| EP-1735300-A1 | THIO-SUBSTITUTED TRICYCLIC AND BICYCLIC AROMATIC METHANESULFINYL DERIVATIVES | CEPHALON FRANCE (FR) | 2006-12-27 | — | — | EP | disclosed |
| US-20050282821-A1 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2005-12-22 | — | — | US | disclosed |
| WO-2005100345-A1 | THIO-SUBSTITUTED TRICYCLIC AND BICYCLIC AROMATIC METHANESULFINYL DERIVATIVES | CEPHALON FRANCE (FR) | 2005-10-27 | — | — | WO | disclosed |
| EP-1589016-A1 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2005-10-26 | — | — | EP | disclosed |
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1285908-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-0430459-B1 | Tetrahydronaphthalene derivatives and preparation thereof | TANABE SEIYAKU CO (JP) | 1994-06-22 | — | — | EP | disclosed |
| US-5206418-A | Thromboxan A2 antagonist | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| US-5206428-A | Anticoagulants | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0430459-A1 | Tetrahydronaphthalene derivatives and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |
| US-4007177-A | BACTERICIDE, ANTIBIOTIC | SANKYO COMPANY LIMITED (JA) | 1977-02-08 | — | — | US | disclosed |