Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21961149 | 0.84 | TSHR (0.57) | TSHRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL1904536 | 0.84 | TSHR (0.57) | TSHRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL8878989 | 0.83 | TSHR (0.44) | TSHRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL8147783 | 0.83 | ALDH1A1 (0.50) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL39201 | 0.83 | TSHR (0.52) | TSHRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL1353325 | 0.83 | TSHR (0.47) | TSHRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL14322500 | 0.83 | TSHR (0.47) | TSHRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL27922019 | 0.82 | TSHR (0.49) | TSHRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL1535968 | 0.82 | TSHR (0.53) | TSHRALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29066790 | 0.81 | TSHR (0.46) | TSHRALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110655456-B | Method for preparing chiral alkyl compound by asymmetric catalytic hydrogenation of E/Z mixed or single-configuration tri-substituted olefin | 浙江大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-110655456-A | Method for preparing chiral alkyl compound by asymmetric catalytic hydrogenation of E/Z mixed or single-configuration tri-substituted olefin | 浙江大学 | 2020-01-07 | — | — | CN | disclosed |
| US-9732078-B2 | Therapeutic use of imidazopyridine derivatives | SANOFI (FR) | 2017-08-15 | — | — | US | disclosed |