Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 15/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.60 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19254305 | 0.89 | CSNK2A1 (0.70) | CSNK2A1MAPTTP53NPSR1USP2 | |
| SCHEMBL297749 | 0.88 | CSNK2A1 (0.87) | CSNK2A1MAPTUSP2LMNATSHR | |
| SCHEMBL19254727 | 0.87 | CSNK2A1 (0.65) | CSNK2A1MAPTTP53NPSR1USP2 | |
| SCHEMBL19254310 | 0.87 | CSNK2A1 (0.72) | CSNK2A1MAPTTP53NPSR1USP2 | |
| SCHEMBL19254726 | 0.84 | CSNK2A1 (0.61) | CSNK2A1MAPTTP53NPSR1USP2 | |
| SCHEMBL19254292 | 0.82 | CSNK2A1 (0.67) | CSNK2A1MAPTTP53NPSR1USP2 | |
| SCHEMBL19254575 | 0.82 | CSNK2A1 (0.67) | CSNK2A1MAPTTP53NPSR1USP2 | |
| SCHEMBL28015906 | 0.81 | CSNK2A1 (0.89) | CSNK2A1MAPTTP53NPSR1USP2 | |
| SCHEMBL3333973 | 0.81 | CSNK2A1 (0.84) | CSNK2A1MAPTUSP2LMNATSHR | |
| SCHEMBL298156 | 0.80 | CSNK2A1 (0.85) | CSNK2A1MAPTTP53NPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |