Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABHD10 | Q9NUJ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564293 | 0.84 | ATM (0.50) | ACACBPPARGPPARAHPGDL3MBTL1 | |
| SCHEMBL15933208 | 0.84 | PPARG (0.48) | ACACBPPARGPPARAHPGDL3MBTL1 | |
| SCHEMBL14590363 | 0.84 | ATM (0.50) | ACACBPPARGPPARAHPGDL3MBTL1 | |
| SCHEMBL6575139 | 0.84 | ATM (0.50) | ACACBPPARGPPARAHPGDL3MBTL1 | |
| SCHEMBL12864879 | 0.83 | KMT2A (0.41) | ACACBPPARGPPARACYP4F2CYP4A11 | |
| SCHEMBL14190608 | 0.82 | ACACB (0.42) | ACACBPPARGPPARAHPGDL3MBTL1 | |
| SCHEMBL28799585 | 0.82 | AGXT (0.42) | ACACBPPARGPPARAHPGDL3MBTL1 | |
| SCHEMBL11615201 | 0.79 | ACACB (0.47) | ACACBPPARGPPARAHPGDTSHR | |
| SCHEMBL12696346 | 0.77 | TBXAS1 (0.53) | ACACBPPARGPPARAHPGDTSHR | |
| SCHEMBL10081972 | 0.77 | TBXAS1 (0.53) | ACACBPPARGPPARAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017135471-A1 | INTEGRIN α4β7 INHIBITOR | ＥＡファーマ株式会社 | 2017-08-10 | — | — | WO | disclosed |