Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251394 | 0.85 | GRM5 (0.38) | GRM5ALDH1A1HSD17B10KDM4EALOX15 | |
| SCHEMBL22752392 | 0.84 | GRM5 (0.40) | GRM5ALDH1A1HSD17B10KDM4EALOX15 | |
| SCHEMBL22752613 | 0.78 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL19251314 | 0.76 | GRM5 (0.40) | GRM5ALDH1A1HSD17B10KDM4EALOX15 | |
| SCHEMBL25735074 | 0.76 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL18935611 | 0.76 | NUDT1 (0.37) | ALDH1A1KDM4EESR1ESR2 | |
| SCHEMBL19254601 | 0.75 | CNR2 (0.42) | — | |
| SCHEMBL9906410 | 0.74 | HSD17B10 (0.45) | GRM5ALDH1A1HSD17B10KDM4EALOX15 | |
| SCHEMBL22752552 | 0.73 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL19464706 | 0.73 | ESR1 (0.33) | ESR1ESR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732078-B2 | Therapeutic use of imidazopyridine derivatives | SANOFI (FR) | 2017-08-15 | — | — | US | disclosed |