Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 9/20 | 0.39 |
| ▸ | EDNRB | P24530 | 8/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 7/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19255048 | 0.85 | LOXL2 (0.42) | LOXL2DAOAOC3 | |
| SCHEMBL19255166 | 0.82 | LOXL2 (0.39) | LOXL2DAOAOC3 | |
| SCHEMBL19255571 | 0.82 | LOXL2 (0.37) | LOXL2DAOAOC3 | |
| SCHEMBL19255398 | 0.80 | LOXL2 (0.38) | LOXL2DAOAOC3 | |
| SCHEMBL19255718 | 0.74 | LOXL2 (0.45) | LOXL2DAOAOC3 | |
| SCHEMBL19255442 | 0.73 | LOXL2 (0.65) | LOXL2DAOAOC3 | |
| Hydrochloric Acid SCHEMBL20699534 | 0.73 | LOXL2 (0.66) | LOXL2DAOAOC3 | |
| SCHEMBL19255400 | 0.70 | LOXL2 (0.52) | LOXL2DAOAOC3 | |
| SCHEMBL19255163 | 0.69 | LOXL2 (0.54) | LOXL2 | |
| SCHEMBL19255067 | 0.69 | LOXL2 (0.55) | LOXL2DAOAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136870-A9 | HALOALLYLAMINE INDOLE AND AZAINDOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2018-02-15 | — | — | WO | disclosed |
| WO-2017136870-A1 | HALOALLYLAMINE INDOLE AND AZAINDOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2017-08-17 | — | — | WO | disclosed |