⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561665 | 0.81 | — | — | |
| SCHEMBL14227052 | 0.81 | ITGB1 (0.42) | — | |
| SCHEMBL15844914 | 0.81 | ITGB1 (0.42) | — | |
| SCHEMBL11505165 | 0.81 | — | — | |
| SCHEMBL15844913 | 0.81 | ITGB1 (0.42) | — | |
| SCHEMBL22421684 | 0.80 | MMP2 (0.31) | — | |
| SCHEMBL2781164 | 0.78 | TDP1 (0.45) | — | |
| SCHEMBL5317745 | 0.78 | TDP1 (0.45) | — | |
| SCHEMBL23586768 | 0.78 | MAPT (0.55) | — | |
| SCHEMBL1661034 | 0.78 | FOLH1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915389-B1 | DIFFERENTIALLY PROTECTED ORTHOGONAL LANTHIONINE TECHNOLOGY | ORAGENICS INC (US) | 2011-06-08 | — | — | EP | disclosed |
| US-20090215985-A1 | DIFFERENTIALLY PROTECTED ORTHOGONAL LANTHIONINE TECHNOLOGY | ORAGENICS, INC. | 2009-08-27 | — | — | US | disclosed |
| US-7521529-B2 | Differentially protected orthogonal lanthionine technology | ORAGENICS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-20070037963-A1 | Lantibiotics; biosynthesis; solid phase synthesis; deblocking, deprotecting | ORAGENICS, INC. | 2007-02-15 | — | — | US | disclosed |