Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19255096 | 0.87 | RIPK1 (0.50) | RIPK1 | |
| SCHEMBL19255655 | 0.82 | RIPK1 (0.55) | RIPK1 | |
| SCHEMBL19255627 | 0.81 | RIPK1 (0.49) | RIPK1 | |
| SCHEMBL29415743 | 0.78 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL19228092 | 0.78 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL19228266 | 0.78 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL22509198 | 0.78 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL19228375 | 0.78 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL19228561 | 0.78 | RIPK1 (0.72) | RIPK1 | |
| SCHEMBL19207459 | 0.77 | RIPK1 (0.72) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136727-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. (US) | 2017-08-10 | — | — | WO | disclosed |