Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.33 |
| ▸ | FDPS | P14324 | 9/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24926234 | 1.00 | PLA2G1B (0.35) | PLA2G1BPLA2G2ATSHRTHRBGGPS1 | |
| SCHEMBL20803799 | 0.90 | PLA2G1B (0.36) | PLA2G1BPLA2G2ATSHRTHRBGGPS1 | |
| SCHEMBL25096432 | 0.79 | DNM1 (0.33) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL28075093 | 0.78 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL27977743 | 0.78 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL20803962 | 0.78 | — | — | |
| SCHEMBL18743796 | 0.77 | DNM1 (0.44) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL20589570 | 0.75 | TSHR (0.53) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL8685403 | 0.75 | TSHR (0.53) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL8687541 | 0.75 | TSHR (0.53) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730934-B2 | Quinazoline derivatives substituted by aniline, preparation method and use thereof | Xuanzhu Pharma Co., Ltd. (CN) | 2017-08-15 | — | — | US | disclosed |