Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106296 | 0.78 | ADORA2A (0.44) | PDE10A | |
| SCHEMBL13106424 | 0.74 | GAA (0.33) | PDE10A | |
| SCHEMBL13106263 | 0.63 | ADORA2A (0.44) | PDE10A | |
| SCHEMBL13106294 | 0.63 | PDE10A (0.40) | PDE10A | |
| SCHEMBL13106319 | 0.63 | ADORA2A (0.44) | PDE10A | |
| SCHEMBL29324494 | 0.62 | PDK1 (0.33) | — | |
| SCHEMBL13106248 | 0.62 | ADORA2A (0.42) | — | |
| SCHEMBL9979917 | 0.62 | USP2 (0.33) | — | |
| SCHEMBL13106308 | 0.61 | ADORA2A (0.41) | PDE10A | |
| SCHEMBL13106303 | 0.61 | ADORA2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |