Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.41 |
| ▸ | KRAS | P01116 | 4/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19211735 | 0.88 | LOXL2 (0.64) | LOXL2DAOAOC3 | |
| Hydrochloric Acid SCHEMBL20699636 | 0.87 | LOXL2 (0.65) | LOXL2DAOAOC3 | |
| SCHEMBL19255578 | 0.81 | LOXL2 (0.51) | LOXL2PTGDR2KRASDAOAOC3 | |
| SCHEMBL19255708 | 0.80 | LOXL2 (0.52) | LOXL2PTGDR2KRASDAOAOC3 | |
| SCHEMBL19211747 | 0.77 | LOXL2 (0.62) | LOXL2PTGDR2DAOAOC3 | |
| Hydrochloric Acid SCHEMBL20699544 | 0.76 | LOXL2 (0.62) | LOXL2DAOAOC3 | |
| SCHEMBL19255408 | 0.76 | LOXL2 (0.54) | LOXL2PTGDR2DAOAOC3 | |
| SCHEMBL19255244 | 0.76 | LOXL2 (0.63) | LOXL2DAOAOC3 | |
| SCHEMBL19255572 | 0.75 | LOXL2 (0.56) | LOXL2PTGDR2DAOAOC3 | |
| SCHEMBL19255199 | 0.75 | LOXL2 (0.56) | LOXL2PTGDR2DAOAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136870-A9 | HALOALLYLAMINE INDOLE AND AZAINDOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2018-02-15 | — | — | WO | disclosed |
| WO-2017136870-A1 | HALOALLYLAMINE INDOLE AND AZAINDOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2017-08-17 | — | — | WO | disclosed |