Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543078 | 0.90 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1EPHX2TSHRTDP1 | |
| SCHEMBL9153257 | 0.88 | EPHX2 (0.46) | ALDH1A1L3MBTL1EPHX2TSHRTDP1 | |
| SCHEMBL17402500 | 0.85 | EPHX2 (0.52) | ALDH1A1L3MBTL1EPHX2TSHRTDP1 | |
| SCHEMBL15869131 | 0.84 | TSHR (0.45) | ALDH1A1L3MBTL1EPHX2TSHRTDP1 | |
| SCHEMBL18641735 | 0.84 | EPHX2 (0.54) | ALDH1A1L3MBTL1EPHX2TSHRTDP1 | |
| SCHEMBL27274906 | 0.84 | EPHX2 (0.54) | ALDH1A1L3MBTL1EPHX2TSHRTDP1 | |
| SCHEMBL3525287 | 0.84 | EPHX2 (0.54) | ALDH1A1L3MBTL1EPHX2TSHRTDP1 | |
| SCHEMBL25269510 | 0.83 | EPHX2 (0.57) | L3MBTL1EPHX2TSHRTDP1TEAD3 | |
| SCHEMBL19032713 | 0.83 | EPHX2 (0.57) | L3MBTL1EPHX2TSHRTDP1TEAD3 | |
| SCHEMBL10081325 | 0.83 | EPHX2 (0.57) | L3MBTL1EPHX2TSHRTDP1TEAD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |