Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 18/20 | 0.71 |
| ▸ | PYGL | P06737 | 1/20 | 0.52 |
| ▸ | PYGM | P11217 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17312379 | 1.00 | RIPK1 (0.71) | RIPK1PYGLPYGM | |
| SCHEMBL17312381 | 1.00 | RIPK1 (0.71) | RIPK1PYGLPYGM | |
| SCHEMBL17321340 | 0.91 | RIPK1 (0.59) | RIPK1 | |
| SCHEMBL17312880 | 0.89 | RIPK1 (0.58) | RIPK1PYGLPYGM | |
| SCHEMBL17312881 | 0.89 | RIPK1 (0.58) | RIPK1PYGLPYGM | |
| SCHEMBL17312868 | 0.88 | RIPK1 (0.56) | RIPK1PYGLPYGM | |
| SCHEMBL21307337 | 0.88 | RIPK1 (0.56) | RIPK1PYGLPYGM | |
| SCHEMBL17312872 | 0.88 | RIPK1 (0.56) | RIPK1PYGLPYGM | |
| SCHEMBL19207603 | 0.87 | RIPK1 (0.73) | RIPK1 | |
| SCHEMBL19207687 | 0.87 | RIPK1 (0.73) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136727-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. (US) | 2017-08-10 | — | — | WO | disclosed |