Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.63 |
| ▸ | RELA | Q04206 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.59 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433887 | 1.00 | LMNA (0.63) | LMNASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL12299687 | 0.95 | LMNA (0.69) | LMNASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL21084423 | 0.95 | LMNA (0.69) | LMNASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL13325825 | 0.95 | LMNA (0.69) | LMNASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL4171854 | 0.95 | LMNA (0.69) | LMNASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL9855583 | 0.95 | LMNA (0.69) | LMNASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL21084486 | 0.95 | LMNA (0.69) | LMNASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL21124189 | 0.95 | LMNA (0.69) | LMNASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL19460698 | 0.95 | LMNA (0.69) | LMNASMN1; SMN2NPC1NFKB1NFKB2 | |
| SCHEMBL16476681 | 0.95 | LMNA (0.69) | LMNASMN1; SMN2NPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106701106-B | Alignment mechanism for optical dyes | 光学转变公司 | 2022-03-29 | — | — | CN | disclosed |
| EP-2358845-B1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL INC (US) | 2014-11-12 | — | — | EP | disclosed |
| US-8828507-B2 | Alignment facilities for optical dyes | TRANSITIONS OPTICAL, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| EP-2358845-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2011-08-24 | — | — | EP | disclosed |
| US-8003005-B2 | Alignment facilities for optical dyes | TRANSITIONS OPTICAL, INC. (US) | 2011-08-23 | — | — | US | disclosed |
| US-20110128457-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| WO-2010065406-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20090146104-A1 | ALIGNMENT FACILITIES FOR OPTICAL DYES | TRANSITIONS OPTICAL, INC. (US) | 2009-06-11 | — | — | US | disclosed |