Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207814 | 0.85 | RIPK1 (0.63) | RIPK1 | |
| SCHEMBL19224543 | 0.81 | RIPK1 (0.44) | RIPK1 | |
| SCHEMBL19255334 | 0.80 | RIPK1 (0.57) | RIPK1 | |
| Hydrochloric Acid SCHEMBL31663495 | 0.80 | RIPK1 (0.43) | RIPK1 | |
| Hydrochloric Acid SCHEMBL19207697 | 0.80 | RIPK1 (0.43) | RIPK1 | |
| SCHEMBL19224546 | 0.79 | RIPK1 (0.53) | RIPK1 | |
| SCHEMBL29596255 | 0.79 | RIPK1 (0.53) | RIPK1 | |
| SCHEMBL23336686 | 0.78 | RIPK1 (0.39) | RIPK1 | |
| SCHEMBL19255644 | 0.77 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL19207947 | 0.76 | RIPK1 (0.73) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136727-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. (US) | 2017-08-10 | — | — | WO | disclosed |