Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271302 | 1.00 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2L3MBTL1POLBPKM | |
| SCHEMBL2712442 | 0.94 | PARP1 (0.34) | ALDH1A1SMN1; SMN2PKMPARP1PIK3CA | |
| SCHEMBL2906775 | 0.94 | PARP1 (0.34) | ALDH1A1SMN1; SMN2PKMPARP1PIK3CA | |
| SCHEMBL19255876 | 0.94 | PARP1 (0.34) | ALDH1A1SMN1; SMN2PKMPARP1PIK3CA | |
| Hydrochloric Acid SCHEMBL28060430 | 0.92 | PARP1 (0.33) | ALDH1A1SMN1; SMN2PKMPARP1PIK3CA | |
| Hydrochloric Acid SCHEMBL14675869 | 0.92 | PARP1 (0.33) | ALDH1A1SMN1; SMN2PKMPARP1PIK3CA | |
| SCHEMBL19257646 | 0.85 | — | — | |
| SCHEMBL19257658 | 0.85 | — | — | |
| SCHEMBL17157178 | 0.81 | FFAR3 (0.37) | — | |
| SCHEMBL17171332 | 0.81 | FFAR3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134547-A1 | TUBULYSIN ANALOGS AND METHODS FOR THEIR PREPARATION | PFIZER INC. (US) | 2017-08-10 | — | — | WO | disclosed |