⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27963333 | 0.98 | KDM4E (0.96) | — | |
| Hydrochloric Acid SCHEMBL8624744 | 0.98 | KDM4E (0.96) | — | |
| Benzene SCHEMBL28205648 | 0.98 | KDM4E (0.96) | — | |
| Dimethylformamide SCHEMBL27620258 | 0.87 | KDM4E (0.76) | — | |
| SCHEMBL8682418 | 0.84 | PKM (0.72) | — | |
| SCHEMBL29015082 | 0.83 | PKM (0.70) | — | |
| SCHEMBL7962955 | 0.82 | — | — | |
| SCHEMBL5725392 | 0.82 | — | — | |
| SCHEMBL1667399 | 0.80 | — | — | |
| Furan-2(5H)-One SCHEMBL28436911 | 0.79 | PKM (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 704 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072591-B | Febuxostat and intermediates and synthesis thereof | 杭州朱养心药业有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-111039891-B | Method for synthesizing febuxostat and intermediate thereof | 杭州朱养心药业有限公司 | 2025-03-28 | — | — | CN | claimed |
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2025-03-13 | — | — | US | claimed |
| CN-119528900-A | Methylthiazole derivative with anti-liver cancer activity and preparation method and application thereof | 河南科技大学 | 2025-02-28 | — | — | CN | claimed |
| CN-119504640-A | Febuxostat preparation technology | 哈药集团技术中心 | 2025-02-25 | — | — | CN | claimed |
| CN-118994140-A | Triazole derivative with antidepressant effect, and preparation method and application thereof | 河南科技大学 | 2024-11-22 | — | — | CN | claimed |
| CN-118994141-A | Phenylthiazole derivative with anti-liver cancer and anti-inflammatory activities and preparation method and application thereof | 河南科技大学 | 2024-11-22 | — | — | CN | claimed |
| CN-110167944-B | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2024-08-23 | — | — | CN | claimed |
| CN-118206505-A | Near infrared fluorescent probe for identifying erythromycin and preparation method and application thereof | 忻州师范学院 | 2024-06-18 | — | — | CN | claimed |
| CN-115772137-B | Preparation method of febuxostat | 济宁晟泰药业有限公司 | 2024-05-10 | — | — | CN | claimed |
| EP-1894568-A1 | Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases | Novartis AG (CH) | 2008-03-05 | — | — | EP | claimed |
| WO-2007136703-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | claimed |
| CN-101020668-A | Process of synthesizing 4-methyl-5-formyl thiazole | UNIV TSINGHUA (CN) | 2007-08-22 | — | — | CN | claimed |
| US-20070032478-A1 | Kinase Inhibitors | ALLERGAN, INC. | 2007-02-08 | — | — | US | claimed |
| WO-2007008895-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2007-01-18 | — | — | WO | claimed |
| WO-2005100330-A1 | PREPARATION OF INTERMEDIATE FOR 3-[2-(4-METHYLTHIAZOLE-5-YL)VINYL] CEPHALOSPORINS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | claimed |
| US-6255339-B1 | PREVENTION PROSGESTERONE RECEPTOR BINDING | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-07-03 | — | — | US | claimed |
| EP-0885893-A1 | NOVEL TETRAHYDRONAPHTHOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0015824-B1 | METAL DITHIOPHOSPHATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ADDITIVES FOR LUBRICATING OILS | OROGIL (FR) | 1982-02-17 | — | — | EP | claimed |
| US-4288335-A | REACTING ESTER WITH PHOSPHORUS SULFIDE, METAL OXIDE | OROGIL (FR) | 1981-09-08 | — | — | US | claimed |