Sugi Predict

Sugi Predict / Compounds / SCHEMBL19256701

SCHEMBL19256701

SCHEMBL19256701

CC(C)(C)OC(=O)N(Cc1cccc(/C(N)=N/O)c1)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 1/20 0.43
▸ GRM2 Q14416 1/20 0.41
▸ F2 P00734 5/20 0.39
▸ PRSS1 P07477 4/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ MEP1B Q16820 1/20 0.37
▸ KDM1A O60341 1/20 0.36
▸ F10 P00742 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ LOXL2 Q9Y4K0 1/20 0.36
▸ PTGES O14684 1/20 0.36
▸ HDAC1 Q13547 2/20 0.35
▸ HDAC3 O15379 1/20 0.35
▸ HDAC2 Q92769 1/20 0.35
▸ NCOR2 Q9Y618 1/20 0.35
▸ BMP1 P13497 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11891918 1.00 SLC7A5 (0.43) SLC7A5GRM2F2PRSS1L3MBTL1
SCHEMBL9968915 0.85 HDAC1 (0.39) SLC7A5F2PRSS1L3MBTL1MEP1B
SCHEMBL9968922 0.85 HDAC1 (0.42) SLC7A5F2PRSS1L3MBTL1RAB9A
SCHEMBL11893184 0.85 PRSS1 (0.48) SLC7A5GRM2F2PRSS1F10
SCHEMBL29573114 0.84 GRM2 (0.42) GRM2F2L3MBTL1RAB9AHDAC1
SCHEMBL6791575 0.84 GRM2 (0.42) GRM2F2L3MBTL1RAB9AHDAC1
SCHEMBL9968923 0.83 HDAC1 (0.43) SLC7A5F2PRSS1L3MBTL1RAB9A
SCHEMBL408595 0.83 HDAC1 (0.41) SLC7A5F2PRSS1L3MBTL1RAB9A
SCHEMBL408596 0.83 HDAC1 (0.41) SLC7A5F2PRSS1L3MBTL1RAB9A
SCHEMBL10170383 0.83 HDAC1 (0.41) SLC7A5F2PRSS1L3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210330671-A1 PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS SANOFI SA (FR) 2021-10-28 — — US disclosed
US-20190262338-A1 PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS SANOFI SA (FR) 2019-08-29 — — US disclosed
US-20190000845-A1 PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS SANOFI SA (FR) 2019-01-03 — — US disclosed
US-9937175-B2 Phenyloxadiazole derivatives as PGDS inhibitors SANOFI (FR) 2018-04-10 — — US disclosed
US-20170231990-A1 PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS SANOFI- AVENTIS (FR) 2017-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190000845-A1 PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS PTGER1, PTGIS, PTGDR SLC7A5 4500/4885GRM2 2256/4885F2 492/4885
US-20190262338-A1 PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS PTGER1, PTGIS, PTGDR SLC7A5 4497/4885GRM2 2230/4885F2 471/4885
US-20210330671-A1 PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS PTGER1, PTGIS, PTGDR SLC7A5 4537/4885GRM2 2267/4885F2 517/4885
US-20170231990-A1 PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS PTGER1, PTGIS, PTGDR SLC7A5 4500/4885GRM2 2256/4885F2 492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.