SCHEMBL19256986

SCHEMBL19256986

Cc1ccc2c(c1)[nH]c1cc(-c3ccccc3)ccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.67
TNKS2 Q9H2K2 3/20 0.60
CDK4 P11802 1/20 0.48
CCND1 P24385 1/20 0.48
FEN1 P39748 1/20 0.47
JAK2 O60674 1/20 0.46
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
NPC1 O15118 2/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
RXFP1 Q9HBX9 1/20 0.44
BCHE P06276 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
EGFR P00533 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19773148 0.91 KIF11 (0.66) KIF11TNKS2CDK4CCND1JAK2
SCHEMBL15002841 0.91 KIF11 (0.61) KIF11TNKS2CDK4CCND1FEN1
SCHEMBL29533133 0.88 TNKS2 (0.61) KIF11TNKS2CDK4CCND1FEN1
SCHEMBL533285 0.88 TNKS2 (0.61) KIF11TNKS2CDK4CCND1FEN1
SCHEMBL29152725 0.86 KIF11 (0.55) KIF11TNKS2KDM4EHPGDNPC1
SCHEMBL20662907 0.85 KIF11 (0.72) KIF11TNKS2KDM4EHPGDHSD17B10
SCHEMBL1900394 0.82 AHR (0.61) KIF11TNKS2CDK4CCND1FEN1
SCHEMBL29724221 0.82 AHR (0.61) KIF11TNKS2CDK4CCND1FEN1
SCHEMBL30959744 0.82 AHR (0.61) KIF11TNKS2CDK4CCND1FEN1
SCHEMBL20290655 0.82 AHR (0.61) KIF11TNKS2CDK4CCND1FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3998321-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE SFC Co., Ltd. (KR) 2022-05-18 EP disclosed
US-20190081251-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE SONY CORPORATION (JP) 2019-03-14 US disclosed
EP-3432376-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE Sony Corporation (JP) 2019-01-23 EP disclosed
US-9771373-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-09-26 US disclosed
US-9732069-B2 Carbazole compound and organic light emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-15 US disclosed