Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703844 | 0.85 | TSHR (0.37) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL28225850 | 0.82 | TSHR (0.41) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL19594830 | 0.81 | TSHR (0.43) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL27101905 | 0.79 | TSHR (0.48) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL8912516 | 0.79 | CA12 (0.55) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL27101906 | 0.78 | MAOA (0.35) | TSHR | |
| SCHEMBL23065597 | 0.78 | TSHR (0.41) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL16782927 | 0.75 | TSHR (0.42) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL26778457 | 0.75 | TSHR (0.42) | TSHRALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL29587773 | 0.74 | TSHR (0.38) | TSHRALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017138855-A1 | METHOD FOR PREPARATION OF LIRAGLUTIDE USING BAL LINKER | POLYPEPTIDE LABORATORIES HOLDING (PPL) AB (SE) | 2017-08-17 | — | — | WO | disclosed |