SCHEMBL19257440

SCHEMBL19257440

CN(C)c1ccc2oc3ccncc3c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.41
CHRM5 P08912 1/20 0.39
CHKA P35790 1/20 0.39
MAPT P10636 5/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
KMT2A Q03164 2/20 0.38
TBK1 Q9UHD2 3/20 0.38
IKBKE Q14164 2/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
MEN1 O00255 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
HBB P68871 1/20 0.36
APP P05067 2/20 0.35
TERT O14746 1/20 0.35
KDM4E B2RXH2 1/20 0.35
SNCA P37840 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16406238 0.80 MAPT (0.34) MAPTSMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL11884986 0.78 ACHE (0.37) MAPTSMN1; SMN2CASP1KDM4E
SCHEMBL15368227 0.77 ACHE (0.50) MAPTSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL15836030 0.77 DYRK1A (0.38) MAPT
SCHEMBL15835994 0.77 DYRK1A (0.38) MAPT
SCHEMBL24057399 0.76 MAPK10 (0.36) NPC1RAB9AKMT2A
SCHEMBL25478046 0.76 MAPK10 (0.36) NPC1RAB9AKMT2A
SCHEMBL25477435 0.76 KDM4E (0.37) MAPTSMN1; SMN2NPC1RAB9AALOX15
SCHEMBL24057770 0.76 MAPK10 (0.36) NPC1RAB9AKMT2A
SCHEMBL6494373 0.75 MAPT (0.53) MAPTSMN1; SMN2NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9735373-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-08-15 US disclosed