Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 5/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.54 |
| ▸ | TOP1 | P11387 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | HPGD | P15428 | 8/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10550996 | 0.89 | KDM4E (0.65) | TOP2ATOP1KDM4EALDH1A1HPGD | |
| SCHEMBL22864334 | 0.89 | LMNA (0.62) | TOP2ATOP2BTOP1KDM4EALDH1A1 | |
| SCHEMBL10570723 | 0.87 | TOP2A (0.53) | TOP2ATOP2BTOP1KDM4EALDH1A1 | |
| SCHEMBL25377579 | 0.85 | KDM4E (0.51) | TOP2ATOP2BTOP1KDM4EALDH1A1 | |
| SCHEMBL10570106 | 0.85 | TOP2A (0.58) | TOP2ATOP2BTOP1KDM4EALDH1A1 | |
| SCHEMBL5595372 | 0.83 | KDM4E (0.49) | TOP2ATOP2BTOP1KDM4EALDH1A1 | |
| SCHEMBL10679871 | 0.83 | KCNH2 (0.61) | TOP2ATOP2BTOP1AADATKCNH2 | |
| SCHEMBL10433824 | 0.82 | KDM4E (0.45) | TOP2ATOP2BTOP1KDM4EALDH1A1 | |
| SCHEMBL10434044 | 0.82 | KDM4E (0.45) | TOP2ATOP2BTOP1KDM4EALDH1A1 | |
| SCHEMBL10550772 | 0.82 | KDM4E (0.45) | TOP2ATOP2BTOP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345594-B1 | SOLUBILIZED FLAVONOID COMPOSITION | TECH INVESTMENTS LC (US) | 2021-11-17 | — | — | EP | disclosed |
| US-20170296668-A1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUND | VIZURI HEALTH SCIENCES CONSUMER HEALTHCARE, INC. | 2017-10-19 | — | — | US | disclosed |
| US-9730953-B2 | Methods of increasing solubility of poorly soluble compounds and methods of making and using formulations of such compound | VIZURI HEALTH SCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170296668-A1 | METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUND | ABCG2, CYP2F1, LSS | TOP2A 2356/4885TOP2B 2643/4885TOP1 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.