Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.53 |
| ▸ | RELA | Q04206 | 4/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18024827 | 0.94 | NFKB1 (0.50) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL22241778 | 0.90 | NFKB1 (0.55) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL2630498 | 0.90 | NFKB1 (0.55) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL2630503 | 0.90 | NFKB1 (0.55) | NFKB1NFKB2RELABTKGAA | |
| Bicarbonate SCHEMBL6014904 | 0.87 | NFKB1 (0.53) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL1927425 | 0.83 | NFKB1 (0.51) | NFKB1NFKB2RELABTKGAA | |
| Methanesulfonic Acid Methyl Ester SCHEMBL3901628 | 0.81 | NFKB1 (0.47) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL18024837 | 0.79 | NFKB1 (0.51) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL6258791 | 0.79 | NFKB1 (0.51) | NFKB1NFKB2RELABTKGAA | |
| SCHEMBL6258795 | 0.79 | NFKB1 (0.51) | NFKB1NFKB2RELABTKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133669-A1 | 5, 7-DIAZAINDOLE AND 5, 7-DIAZAINDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| CN-1293057-C | Ethylenediamine derivatives | DAIICHI SEIYAKU CO (JP) | 2007-01-03 | — | — | CN | disclosed |
| CN-1438993-A | Ethylenediamine derivatives | DAIICHI SEIYAKU CO (JP) | 2003-08-27 | — | — | CN | disclosed |