SCHEMBL19258546

SCHEMBL19258546

O=NC12CC3CC(C1)CC(NCC(=O)N1CCCC1)(C3)C2

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 8/20 0.68
DPP9 Q86TI2 11/20 0.50
DPP8 Q6V1X1 10/20 0.50
GLMN Q92990 1/20 0.50
FAP Q12884 1/20 0.44
BPTF Q12830 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1038132 0.82 DPP4 (0.73) DPP4DPP9DPP8GLMNFAP
SCHEMBL30730737 0.82 DPP4 (0.73) DPP4DPP9DPP8GLMNFAP
SCHEMBL3160947 0.81 DPP4 (1.00) DPP4DPP9DPP8GLMNFAP
SCHEMBL18373779 0.79 DPP4 (0.68) DPP4DPP9DPP8GLMNFAP
SCHEMBL24610704 0.73 DPP4 (0.59) DPP4DPP9DPP8GLMNFAP
SCHEMBL5804593 0.70 DPP9 (0.55) DPP4DPP9DPP8GLMNFAP
SCHEMBL5789566 0.66 DPP9 (0.60) DPP4DPP9DPP8GLMNFAP
SCHEMBL5803813 0.64 DPP4 (0.87) DPP4DPP9DPP8FAP
SCHEMBL5803391 0.64 DPP4 (0.87) DPP4DPP9DPP8FAP
SCHEMBL5803394 0.64 DPP4 (0.87) DPP4DPP9DPP8FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1786401-B1 FAST RELEASE COMPOSITION INCLUDING MELT GRANULES OF A MOISTURE SENSITIVE DRUG AND PROCESS FOR MANUFACTURING THEREOF NOVARTIS AG (CH) 2017-08-16 EP disclosed