Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.57 |
| ▸ | ACR | P10323 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17696399 | 0.88 | PRSS1 (0.46) | PRSS1ACRKMT2ARAB9AL3MBTL1 | |
| SCHEMBL21396265 | 0.87 | PRSS1 (0.71) | PRSS1ACRKMT2ARAB9AL3MBTL1 | |
| SCHEMBL12353129 | 0.87 | PRSS1 (0.71) | PRSS1ACRKMT2ARAB9AL3MBTL1 | |
| SCHEMBL25500942 | 0.87 | PRSS1 (0.71) | PRSS1ACRKMT2ARAB9AL3MBTL1 | |
| SCHEMBL26237363 | 0.87 | PRSS1 (0.71) | PRSS1ACRKMT2ARAB9AL3MBTL1 | |
| SCHEMBL21185827 | 0.87 | PRSS1 (0.71) | PRSS1ACRKMT2ARAB9AL3MBTL1 | |
| SCHEMBL2886812 | 0.85 | MAPT (0.57) | PRSS1ACRKMT2ARAB9AL3MBTL1 | |
| SCHEMBL5567267 | 0.85 | MAPT (0.57) | PRSS1ACRKMT2ARAB9AL3MBTL1 | |
| SCHEMBL2886815 | 0.85 | MAPT (0.57) | PRSS1ACRKMT2ARAB9AL3MBTL1 | |
| SCHEMBL15810560 | 0.80 | MAPT (0.47) | PRSS1ACRKMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623451-B1 | COMPOUND | MERCK PATENT GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| EP-3458549-B1 | LIQUID-CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| EP-3400270-B1 | DEVICE FOR REGULATING ENTRY OF LIGHT | MERCK PATENT GMBH (DE) | 2020-04-29 | — | — | EP | disclosed |
| EP-3623451-A1 | COMPOUND | Merck Patent GmbH (DE) | 2020-03-18 | — | — | EP | disclosed |
| EP-3083885-B1 | WINDOW | MERCK PATENT GMBH (DE) | 2019-10-09 | — | — | EP | disclosed |
| WO-2017137145-A1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | WO | disclosed |