SCHEMBL2886812

SCHEMBL2886812

Nc1ccc(/N=N/c2ccc(OC(=O)c3ccc(/N=N/c4ccc(N)c5ccccc45)cc3)cc2)c2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
MEN1 O00255 1/20 0.57
NPC1 O15118 1/20 0.57
MAPK1 P28482 1/20 0.57
KMT2A Q03164 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
PRSS1 P07477 8/20 0.48
ACR P10323 5/20 0.48
TMPRSS15 P98073 2/20 0.48
F2 P00734 4/20 0.48
PRSS2 P07478 4/20 0.48
PRSS3 P35030 4/20 0.48
SENP3 Q9H4L4 3/20 0.47
SENP2 Q9HC62 3/20 0.47
SENP1 Q9P0U3 3/20 0.47
SENP7 Q9BQF6 3/20 0.47
SUMO2 P61956 2/20 0.47
SUMO1 P63165 2/20 0.47
PARP10 Q53GL7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2886815 1.00 MAPT (0.57) MAPTL3MBTL1MEN1NPC1MAPK1
SCHEMBL5567267 1.00 MAPT (0.57) MAPTL3MBTL1MEN1NPC1MAPK1
SCHEMBL19258831 0.85 PRSS1 (0.57) MAPTL3MBTL1MEN1NPC1MAPK1
SCHEMBL12071728 0.82 MAPT (0.55) MAPTL3MBTL1MEN1NPC1MAPK1
SCHEMBL12069722 0.82 MAPT (0.55) MAPTL3MBTL1MEN1NPC1MAPK1
SCHEMBL3694949 0.80 MEN1 (0.89) MAPTL3MBTL1MEN1NPC1MAPK1
SCHEMBL3694952 0.80 MEN1 (0.89) MAPTL3MBTL1MEN1NPC1MAPK1
SCHEMBL3694948 0.80 MEN1 (0.89) MAPTL3MBTL1MEN1NPC1MAPK1
SCHEMBL14130027 0.78 MAPT (0.66) MAPTL3MBTL1MEN1KMT2ATDP1
SCHEMBL27279499 0.78 MAPT (0.66) MAPTL3MBTL1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1753825-B1 POLYMERIZABLE DICHROMOPHORIC DICHROIC AZO DYES ROLIC AG (CH) 2015-10-14 EP disclosed
EP-1753825-B1 POLYMERIZABLE DICHROMOPHORIC DICHROIC AZO DYES ROLIC AG (CH) 2015-10-14 EP disclosed
CN-1950463-B Polymerizable dichromophore dichroic azo dyes ROLIC AG 2011-06-29 CN disclosed
US-7811642-B2 sufficient solubility, high coloring power, high order parameter; mesogenic mixtures; polarizer, optical filter, orientation layer, security device; acrylic ester, vinyl ester, vinyl ether, or epoxy polymerizable end groups; ROLIC AG (CH) 2010-10-12 US disclosed
US-7811642-B2 sufficient solubility, high coloring power, high order parameter; mesogenic mixtures; polarizer, optical filter, orientation layer, security device; acrylic ester, vinyl ester, vinyl ether, or epoxy polymerizable end groups; ROLIC AG (CH) 2010-10-12 US disclosed
US-7811642-B2 sufficient solubility, high coloring power, high order parameter; mesogenic mixtures; polarizer, optical filter, orientation layer, security device; acrylic ester, vinyl ester, vinyl ether, or epoxy polymerizable end groups; ROLIC AG (CH) 2010-10-12 US disclosed
US-20080001120-A1 sufficient solubility, high coloring power, high order parameter; mesogenic mixtures; polarizer, optical filter, orientation layer, security device; acrylic ester, vinyl ester, vinyl ether, or epoxy polymerizable end groups; ROLIC AG (CH) 2008-01-03 US disclosed
US-20080001120-A1 sufficient solubility, high coloring power, high order parameter; mesogenic mixtures; polarizer, optical filter, orientation layer, security device; acrylic ester, vinyl ester, vinyl ether, or epoxy polymerizable end groups; ROLIC AG (CH) 2008-01-03 US disclosed
US-20080001120-A1 sufficient solubility, high coloring power, high order parameter; mesogenic mixtures; polarizer, optical filter, orientation layer, security device; acrylic ester, vinyl ester, vinyl ether, or epoxy polymerizable end groups; ROLIC AG (CH) 2008-01-03 US disclosed
CN-1950463-A Polymerizable dichromophore dichroic azo dyes ROLIC AG (CH) 2007-04-18 CN disclosed
EP-1593713-A1 Polymerizable dichromophoric dichroic azo dyes Rolic AG (CH) 2005-11-09 EP disclosed