Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259135 | 0.83 | RPS6KA5 (0.37) | RPS6KA5MAPTCDC7GRIN2BRPS6KA4 | |
| SCHEMBL19250590 | 0.77 | GRIN1 (0.34) | GRIN2BCYP1A2 | |
| SCHEMBL1150175 | 0.68 | FGFR1 (0.47) | CYP1A2 | |
| SCHEMBL16302854 | 0.67 | CYP1A2 (0.41) | GRIN2BCYP1A2 | |
| SCHEMBL17055716 | 0.66 | CYP19A1 (0.45) | RPS6KA5MAPTCYP1A2 | |
| SCHEMBL29439025 | 0.66 | PIK3CA (0.41) | RPS6KA5 | |
| SCHEMBL7924961 | 0.65 | CYP1A2 (0.42) | MAPTGRIN2BCYP1A2 | |
| SCHEMBL16302889 | 0.64 | CYP1A2 (0.39) | GRIN2BCYP1A2 | |
| SCHEMBL19258499 | 0.64 | PDE10A (0.34) | — | |
| SCHEMBL19258476 | 0.63 | GRIN1 (0.33) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133657-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |