Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 10/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259088 | 0.80 | PDE10A (0.45) | PDE10A | |
| SCHEMBL19250590 | 0.78 | GRIN1 (0.34) | PDE10A | |
| SCHEMBL19258476 | 0.75 | GRIN1 (0.33) | — | |
| SCHEMBL19258560 | 0.71 | GRIN1 (0.34) | — | |
| SCHEMBL10124285 | 0.71 | NR3C1 (0.50) | — | |
| SCHEMBL19258556 | 0.70 | MAP3K14 (0.30) | — | |
| SCHEMBL19259012 | 0.69 | MEN1 (0.32) | — | |
| SCHEMBL29439025 | 0.64 | PIK3CA (0.41) | — | |
| SCHEMBL19259008 | 0.64 | RPS6KA5 (0.40) | — | |
| SCHEMBL7927906 | 0.64 | HDAC8 (0.39) | HDAC8KDM4ELMNAPOLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133657-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |