Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259180 | 1.00 | PTGS2 (0.32) | PTGS2 | |
| SCHEMBL17178021 | 0.78 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL22044990 | 0.75 | ESR2 (0.41) | — | |
| SCHEMBL30366521 | 0.73 | — | — | |
| SCHEMBL23933987 | 0.73 | PTGS2 (0.32) | PTGS2 | |
| SCHEMBL17162607 | 0.72 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL17162603 | 0.72 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL17162606 | 0.72 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL9253791 | 0.69 | — | — | |
| SCHEMBL8265849 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831839-B1 | C-3 AND C-17 MODIFIED TRITERPENOIDS AS HIV-1 INHIBITORS | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2023-07-26 | — | — | EP | disclosed |
| EP-3831839-A2 | C-3 AND C-17 MODIFIED TRITERPENOIDS AS HIV-1 INHIBITORS | ViiV Healthcare UK (No.5) Limited (GB) | 2021-06-09 | — | — | EP | disclosed |
| WO-2017134596-A1 | C-3 AND C-17 MODIFIED TRITERPENOIDS AS HIV-1 INHIBITORS | VIIV Healthcare UK (No.5) Limited (GB) | 2017-08-10 | — | — | WO | disclosed |