Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.81 |
| ▸ | NAALAD2 | Q9Y3Q0 | 7/20 | 0.81 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12332363 | 1.00 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18636844 | 1.00 | FOLH1 (0.81) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL18161468 | 0.90 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14102870 | 0.90 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL12145776 | 0.90 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14102890 | 0.90 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL1377049 | 0.90 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL1374248 | 0.89 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL21321511 | 0.89 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19209754 | 0.89 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2774608-B1 | Drug loaded polymeric nanoparticles and methods of making and using same | PFIZER (US) | 2019-11-20 | — | — | EP | disclosed |
| EP-2285350-B1 | METHODS FOR THE PREPARATION OF TARGETING AGENT FUNCTIONALIZED DIBLOCK COPOLYMERS FOR USE IN FABRICATION OF THERAPEUTIC NANOPARTICLES | PFIZER (US) | 2017-11-15 | — | — | EP | disclosed |
| EP-2644594-B1 | Cancer Cell Targeting Using Nanoparticles | PFIZER (US) | 2017-08-23 | — | — | EP | disclosed |
| WO-2017137953-A1 | THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING SAME | PFIZER INC. (US) | 2017-08-17 | — | — | WO | disclosed |