SCHEMBL19259396

SCHEMBL19259396

C/C=C/C(=O)OC1[C@H](C)CCC[C@@H]1C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.31
GSTP1 P09211 1/20 0.31
ATM Q13315 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19259350 1.00 EPHX1 (0.31) EPHX1GSTP1ATMTAS1R3TAS1R1
SCHEMBL19275519 1.00 EPHX1 (0.31) EPHX1GSTP1ATMTAS1R3TAS1R1
SCHEMBL19275488 1.00 EPHX1 (0.31) EPHX1GSTP1ATMTAS1R3TAS1R1
SCHEMBL19275693 0.92 ALDH1A1 (0.34) ATM
SCHEMBL19259394 0.92 ALDH1A1 (0.34) ATM
SCHEMBL19275696 0.92 ALDH1A1 (0.34) ATM
SCHEMBL19259357 0.92 ALDH1A1 (0.34) ATM
SCHEMBL19259360 0.85
SCHEMBL19275694 0.85
SCHEMBL10537678 0.83 HCAR2 (0.48) EPHX1ATMTAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3416943-A1 ORGANIC COMPOUNDS Givaudan SA (CH) 2018-12-26 EP disclosed
WO-2017140733-A1 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2017-08-24 WO disclosed