SCHEMBL1925963

SCHEMBL1925963

Cc1cccc(Cc2cccc(C)c2N=C=O)c1N=C=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.60
GABRB2 P47870 4/20 0.60
CYP3A4 P08684 4/20 0.44
TSHR P16473 2/20 0.35
TRPA1 O75762 1/20 0.35
GPR84 Q9NQS5 1/20 0.34
MEN1 O00255 1/20 0.33
HSP90AA1 P07900 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
CYP2C19 P33261 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
CTBP2 P56545 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1022432 0.89 GABRA1 (0.78) GABRA1GABRB2CYP3A4TRPA1MEN1
SCHEMBL31152354 0.89 GABRA1 (0.78) GABRA1GABRB2CYP3A4TRPA1MEN1
SCHEMBL8525620 0.87 GABRA1 (0.58) GABRA1GABRB2CYP3A4TSHRTRPA1
SCHEMBL16279633 0.86 GABRA1 (0.46) GABRA1GABRB2CYP3A4TSHRTRPA1
SCHEMBL10729869 0.85 GABRA1 (0.49) GABRA1GABRB2CYP3A4TSHRCYP2C19
SCHEMBL28028234 0.85 GABRA1 (0.56) GABRA1GABRB2CYP3A4TRPA1MEN1
SCHEMBL8156690 0.84 GABRA1 (0.59) GABRA1GABRB2CYP3A4TSHRTRPA1
SCHEMBL374209 0.83 GABRA1 (0.56) GABRA1GABRB2CYP3A4TSHRTRPA1
SCHEMBL11767094 0.83 GABRA1 (0.50) GABRA1GABRB2CYP3A4TRPA1KMT2A
SCHEMBL16279681 0.83 GABRA1 (0.46) GABRA1GABRB2CYP3A4TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114195977-A Crosslinked biobased hydrophilic foams 约翰·I·纳诺斯 2022-03-18 CN disclosed
CN-114106551-A Clean biobased polyoxyalkylene glycol polyols 约翰·I·纳诺斯 2022-03-01 CN disclosed
EP-3574029-B1 UREA-GROUP- AND/OR URETHANE-GROUP-CONTAINING AMIDES AS AND IN RHEOLOGY CONTROL AGENTS, THEIR PREPARATION AND THEIR USE BYK CHEMIE GMBH (DE) 2021-01-20 EP disclosed
WO-2018138236-A1 UREA-GROUP- AND/OR URETHANE-GROUP-CONTAINING AMIDES AS AND IN RHEOLOGY CONTROL AGENTS, THEIR PREPARATION AND THEIR USE BYK-CHEMIE GMBH (DE) 2018-08-02 WO disclosed
US-9440326-B2 Non-planar glass polishing pad and method of manufacture JH RHODES COMPANY, INC. (US) 2016-09-13 US disclosed
US-9050697-B2 Self-conditioning polishing pad and a method of making the same JH RHODES COMPANY, INC. (US) 2015-06-09 US disclosed
US-20140024296-A1 NON-PLANAR GLASS POLISHING PAD AND METHOD OF MANUFACTURE JH RHODES COMPANY, INC. 2014-01-23 US disclosed
US-20130252519-A1 SELF-CONDITIONING POLISHING PAD AND A METHOD OF MAKING THE SAME JH RHODES COMPANY, INC. (US) 2013-09-26 US disclosed
WO-2012138705-A2 A SELF-CONDITIONING POLISHING PAD AND A METHOD OF MAKING THE SAME UNIVERSAL PHOTONICS, INC. (US) 2012-10-11 WO disclosed
EP-1777246-B1 Polymers containing amide groups for controlling rheology BYK CHEMIE GMBH (DE) 2012-06-06 EP disclosed
US-20040127674-A1 Polymeric urea-urethane rheology control agents and a process for their preparation BYK-CHEMIE GMBH (DE) 2004-07-01 US disclosed
EP-1396510-A1 Polymeric urea-urethanes as thickener and process for its preparation Byk-Chemie GmbH (DE) 2004-03-10 EP disclosed
EP-0590803-A1 Reinforced reaction injection moulded polyurea elastomer Huntsman Corporation (US) 1994-04-06 EP disclosed
EP-0556969-A1 Polyurea elastomers made using polyoxyalkylene tetra- or higher functional amine chain extenders Huntsman Corporation (US) 1993-08-25 EP disclosed
EP-0547743-A2 Amino polysiloxane based polymers TEXACO CHEMICAL COMPANY (US) 1993-06-23 EP disclosed
EP-0215112-B1 A PROCESS FOR PREPARING POLYUREA AND/OR POLYUREA-POLYURETHANE POLYMERS THE DOW CHEMICAL COMPANY (US) 1991-05-29 EP disclosed
EP-0215112-A4 A PROCESS FOR PREPARING POLYUREA AND/OR POLYUREA-POLYURETHANE POLYMERS. DOW CHEMICAL CO (US) 1987-08-24 EP disclosed
US-4686242-A AMINES AND ISOCYANATES THE DOW CHEMICAL COMPANY (US) 1987-08-11 US disclosed
EP-0215112-A1 A PROCESS FOR PREPARING POLYUREA AND/OR POLYUREA-POLYURETHANE POLYMERS. DOW CHEMICAL CO (US) 1987-03-25 EP disclosed
WO-1986005795-A1 A PROCESS FOR PREPARING POLYUREA AND/OR POLYUREA-POLYURETHANE POLYMERS THE DOW CHEMICAL COMPANY (US) 1986-10-09 WO disclosed