Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19263276 | 0.88 | MAPT (0.45) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL19263307 | 0.87 | MAPT (0.56) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL19263008 | 0.82 | MAPT (0.45) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL19263274 | 0.82 | MAPT (0.45) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL19263270 | 0.81 | NPC1 (0.46) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL19263012 | 0.81 | MAPT (0.44) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL19263284 | 0.81 | POLB (0.53) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL19263036 | 0.80 | CA12 (0.45) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL19263005 | 0.79 | MAPT (0.43) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL19263234 | 0.79 | MAPT (0.43) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738673-B1 | Ferrocene derivative, preparation method and use thereof | XIAMEN INSTITUTE OF RARE EARTH MATERIALS (CN) | 2017-08-22 | — | — | US | disclosed |