Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 10/20 | 0.60 |
| ▸ | CLK2 | P49760 | 10/20 | 0.57 |
| ▸ | CLK3 | P49761 | 10/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 10/20 | 0.57 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19263318 | 0.95 | WNT1 (0.59) | WNT1CLK2CLK3DYRK1A | |
| SCHEMBL19263362 | 0.92 | WNT1 (0.71) | WNT1CLK2CLK3DYRK1ATGFBR1 | |
| SCHEMBL20179056 | 0.92 | WNT1 (0.50) | WNT1CLK2CLK3DYRK1ATGFBR1 | |
| SCHEMBL20762772 | 0.90 | WNT1 (0.59) | WNT1CLK2CLK3DYRK1ATGFBR1 | |
| SCHEMBL19263333 | 0.88 | WNT1 (0.63) | WNT1CLK2CLK3DYRK1ATGFBR1 | |
| SCHEMBL20381325 | 0.88 | WNT1 (0.63) | WNT1CLK2CLK3DYRK1ATGFBR1 | |
| SCHEMBL19263316 | 0.88 | WNT1 (0.62) | WNT1CLK2CLK3DYRK1ATGFBR1 | |
| SCHEMBL20762664 | 0.88 | WNT1 (0.59) | WNT1CLK2CLK3DYRK1ATGFBR1 | |
| SCHEMBL19263348 | 0.87 | WNT1 (0.61) | WNT1CLK2CLK3DYRK1ATGFBR1 | |
| SCHEMBL17555584 | 0.86 | WNT1 (0.79) | WNT1CLK2CLK3DYRK1ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738638-B2 | 2-(1H-indazol-3-yl)-3H-imidazo[4,5-B]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2017-08-22 | — | — | US | disclosed |