Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 17/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 17/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19265281 | 0.89 | AVPR2 (0.60) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL3446947 | 0.88 | AVPR2 (0.72) | AVPR2AVPR1A | |
| SCHEMBL3446949 | 0.88 | AVPR2 (0.72) | AVPR2AVPR1A | |
| SCHEMBL3446952 | 0.88 | AVPR2 (0.72) | AVPR2AVPR1A | |
| SCHEMBL19265280 | 0.86 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL3446893 | 0.82 | AVPR2 (0.66) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL19265172 | 0.81 | AVPR2 (0.59) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL4493699 | 0.79 | AVPR2 (0.59) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL8235953 | 0.79 | AVPR2 (0.59) | AVPR2AVPR1ATP53MAPT | |
| SCHEMBL3986162 | 0.79 | AVPR2 (0.61) | AVPR2AVPR1ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408751-B1 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |