Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 16/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19738877 | 0.83 | TLR8 (0.42) | TLR8 | |
| SCHEMBL19416398 | 0.79 | TLR8 (0.41) | TLR8TLR7ALOX5 | |
| SCHEMBL19416514 | 0.79 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL19416470 | 0.78 | TLR8 (0.41) | TLR8TLR7 | |
| SCHEMBL19416269 | 0.78 | TLR8 (0.36) | TLR8TLR7 | |
| SCHEMBL19265549 | 0.78 | TLR8 (0.35) | TLR8 | |
| SCHEMBL19416304 | 0.77 | ESR1 (0.38) | TLR8TLR7 | |
| SCHEMBL18771975 | 0.77 | TLR8 (0.45) | TLR8TLR7 | |
| SCHEMBL18772082 | 0.77 | TLR8 (0.40) | TLR8TLR7 | |
| SCHEMBL19265579 | 0.76 | TLR8 (0.48) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3207930-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |