Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 8/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19499906 | 0.92 | KCNH2 (0.46) | HSD11B1RARBRARAMEN1ALDH1A1 | |
| SCHEMBL13322019 | 0.90 | KCNH2 (0.57) | ALDH1A1KCNH2HSD17B10HTR2ASTS | |
| SCHEMBL15076231 | 0.90 | HSD11B1 (0.58) | HSD11B1RARBRARAMEN1ALDH1A1 | |
| SCHEMBL3146748 | 0.88 | KCNH2 (0.51) | HSD11B1RARBRARAMEN1ALDH1A1 | |
| SCHEMBL7654592 | 0.88 | KCNH2 (0.51) | HSD11B1RARBRARAMEN1ALDH1A1 | |
| SCHEMBL14063940 | 0.87 | RARB (0.57) | HSD11B1RARBRARAMEN1ALDH1A1 | |
| SCHEMBL23763587 | 0.85 | HSD17B10 (0.50) | RARBRARAMEN1ALDH1A1MAPT | |
| SCHEMBL21842600 | 0.85 | HSD17B10 (0.50) | RARBRARAMEN1ALDH1A1MAPT | |
| SCHEMBL16253925 | 0.85 | RARB (0.56) | HSD11B1RARBRARAMEN1ALDH1A1 | |
| SCHEMBL25973832 | 0.85 | RARB (0.56) | HSD11B1RARBRARAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217674-B1 | ELECTROACTIVE MATERIALS | DU PONT (US) | 2017-08-23 | — | — | EP | disclosed |