Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Piperidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL10332243 | 1.00 | ALDH1A1 (0.56) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Piperidine SCHEMBL29043025 | 1.00 | ALDH1A1 (0.56) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Piperidine SCHEMBL1049754 | 0.97 | ALDH1A1 (0.53) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Pyrrolidine SCHEMBL2797002 | 0.97 | — | — | |
| Piperidine SCHEMBL10969397 | 0.94 | ALDH1A1 (0.50) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Piperidine SCHEMBL15571381 | 0.94 | ALDH1A1 (0.50) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Piperidine SCHEMBL15571721 | 0.94 | ALDH1A1 (0.50) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Pyrrolidine SCHEMBL27499862 | 0.94 | ALDH1A1 (0.47) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Acetic Acid SCHEMBL29130314 | 0.94 | SMN1; SMN2 (0.47) | ALDH1A1FFAR3LCKFYNSMN1; SMN2 | |
| Piperidine SCHEMBL27748310 | 0.90 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2CXCR4CA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2216 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250362278-A1 | MASS SPECTROMETRY OF MRNA | MODERNATX, INC. (US) | 2025-11-27 | — | — | US | claimed |
| CN-116621830-B | Double-targeting polyhydroxy alkaloid compound and preparation method and application thereof | 中国医学科学院药用植物研究所 | 2025-06-13 | — | — | CN | claimed |
| CN-120022226-A | Radiotherapy sensitization microneedle and application thereof | 苏州大学 | 2025-05-23 | — | — | CN | claimed |
| WO-2024246617-A1 | ADEMAGLITAZONE SYNTHETIC LIGAND OF THE GAMMA RECEPTOR ACTIVATED BY PEROXISOMAL PROLIFERATORS WITH INSULIN-SENSITIZING ACTIVITY AND LOW ADIPOGENIC CAPACITY, AND ITS USE IN THE PHARMACOLOGICAL TREATMENT OF TYPE 2 DIABETES MELLITUS AND INSULIN RESISTANCE INDUCED BY OBESITY | UNIVERSITA' DEGLI STUDI MAGNA GRAECIA DI CATAZANRO (IT) | 2024-12-05 | — | — | WO | claimed |
| CN-119059885-A | Method for extracting high-purity o-m-para-phenol from mixed cresol | 盐城工学院 | 2024-12-03 | — | — | CN | claimed |
| EP-4426853-A1 | MASS SPECTROMETRY OF MRNA | ModernaTX, Inc. (US) | 2024-09-11 | — | — | EP | claimed |
| CN-117486715-A | Synthetic method of vegetable pest sex pheromone (3E, 8Z, 11Z) -tetradecatriene acetate | 江苏宁录科技股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117050009-A | Preparation method of 4-trifluoromethyl pyridine intermediate core parent nucleus and derivatives thereof | 台州臻挚生物科技有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-116621830-A | Double-targeting polyhydroxy alkaloid compound and preparation method and application thereof | 中国医学科学院药用植物研究所 | 2023-08-22 | — | — | CN | claimed |
| CN-113549007-B | Preparation method of piperidine acetate compound | 清华大学 | 2023-07-18 | — | — | CN | claimed |
| EP-0124742-B1 | PROCESS FOR THE PREPARATION OF SYMMETRIC 1,4-DIHYDROPYRIDINE-CARBOXYLIC ESTERS | BAYER AG (DE) | 1988-08-31 | — | — | EP | claimed |
| EP-0090150-B1 | PROCESS FOR PREPARING 4-HYDROXY-2,5-DIMETHYL-2,3-DIHYDROFURAN-3-ONE | FIRMENICH SA (CH) | 1986-11-20 | — | — | EP | claimed |
| EP-0189071-A2 | Imidazoalkylcarboxylic-acid derivatives, process for their preparation and their use in the preparation of pharmaceutically active compounds | BAYER AG (DE) | 1986-07-30 | — | — | EP | claimed |
| US-4600778-A | Process for the preparation of 1,4-dihydropyridinedicarboxylic esters | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-15 | — | — | US | claimed |
| EP-0165006-A2 | Processes for preparing substituted halomethyl-s-triazines | Polychrome Corporation (US) | 1985-12-18 | — | — | EP | claimed |
| US-4559401-A | Process for preparing chromophore-substituted vinyl-halomethyl-s-triazines | POLYCHROME CORPORATION (US) | 1985-12-17 | — | — | US | claimed |
| EP-0063323-B1 | 5-SUBSTITUTED 4-OXO-PGI1 DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1985-10-30 | — | — | EP | claimed |
| US-4520018-A | 5-Substituted-4-oxo-PGI1 derivatives, PGI1 compounds of similar structure, their pharmaceutical methods and process for the preparation of said compounds | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1985-05-28 | — | — | US | claimed |
| US-4480111-A | CATALYTIC HYDROGENOLYSIS OF ALKALI(OR ALKALI EARTH) METAL DERIVATIVE OF FRUCTOSE MONO(OR DI) PHOSPHATE | FIRMENICH SA (CH) | 1984-10-30 | — | — | US | claimed |
| EP-0063323-A1 | 5-Substituted 4-oxo-PGI1 derivatives, their preparation and pharmaceutical compositions | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1982-10-27 | — | — | EP | claimed |