Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19269018 | 0.78 | KDM4E (0.35) | KDM4ECYP3A4CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL21535205 | 0.70 | KDM4E (0.43) | KDM4ECYP3A4CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL17265807 | 0.70 | MAPT (0.33) | KDM4EHSD17B10DYRK1A | |
| SCHEMBL19268434 | 0.66 | — | — | |
| SCHEMBL2149910 | 0.66 | CYP2A6 (0.54) | KDM4ECYP3A4CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL20418062 | 0.65 | — | — | |
| SCHEMBL15834785 | 0.63 | DYRK1A (0.41) | KDM4ECYP3A4CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL29511331 | 0.63 | DYRK1A (0.41) | KDM4ECYP3A4CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL10885246 | 0.63 | KDM4E (0.37) | KDM4EHSD17B10DYRK1A | |
| SCHEMBL17051493 | 0.62 | CYP3A4 (0.48) | KDM4ECYP3A4CYP2D6CYP2A6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | THE SCRIPPS RESEARCH INSTITUTE | 2020-10-08 | — | — | US | disclosed |
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | ALDH1A2, DDT, CLTB | KDM4E 3074/4885CYP3A4 169/4885CYP2D6 274/4885 |
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | CYBA, DDT, DRD1 | KDM4E 2858/4885CYP3A4 452/4885CYP2D6 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.