Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.76 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500016 | 1.00 | ESR1 (1.00) | ESR1ESR2AGTR2 | |
| SCHEMBL19131502 | 1.00 | ESR1 (1.00) | ESR1ESR2AGTR2 | |
| SCHEMBL26537800 | 0.94 | ESR1 (0.88) | ESR1ESR2AGTR2 | |
| SCHEMBL26539705 | 0.93 | ESR1 (0.88) | ESR1ESR2AGTR2 | |
| SCHEMBL30648937 | 0.93 | ESR1 (0.87) | ESR1ESR2AGTR2 | |
| SCHEMBL21253418 | 0.93 | ESR1 (0.87) | ESR1 | |
| SCHEMBL26187538 | 0.93 | ESR1 (0.87) | ESR1ESR2AGTR2 | |
| SCHEMBL31739221 | 0.93 | ESR1 (0.87) | ESR1 | |
| SCHEMBL19132000 | 0.93 | ESR1 (0.87) | ESR1 | |
| SCHEMBL23163032 | 0.92 | ESR1 (0.86) | ESR1ESR2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524600-B1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS | SANOFI SA (FR) | 2021-11-17 | — | — | EP | disclosed |
| EP-3416962-B1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES AS ESTROGEN RECEPTOR MODULATORS | SANOFI SA (FR) | 2021-05-05 | — | — | EP | disclosed |
| EP-3524600-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS | Sanofi (FR) | 2019-08-14 | — | — | EP | disclosed |
| WO-2017140669-A1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES AS ESTROGEN RECEPTOR MODULATORS | SANOFI (FR) | 2017-08-24 | — | — | WO | disclosed |