Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.88 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.77 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19273601 | 0.93 | ESR1 (1.00) | ESR1ESR2AGTR2 | |
| SCHEMBL19131502 | 0.93 | ESR1 (1.00) | ESR1ESR2AGTR2 | |
| SCHEMBL29500016 | 0.93 | ESR1 (1.00) | ESR1ESR2AGTR2 | |
| SCHEMBL23163032 | 0.93 | ESR1 (0.86) | ESR1ESR2AGTR2 | |
| SCHEMBL23162929 | 0.93 | ESR1 (0.86) | ESR1ESR2AGTR2 | |
| SCHEMBL29836629 | 0.93 | ESR1 (0.86) | ESR1ESR2AGTR2 | |
| SCHEMBL22368444 | 0.93 | ESR1 (0.88) | ESR1ESR2AGTR2 | |
| SCHEMBL23335833 | 0.91 | ESR1 (0.89) | ESR1ESR2AGTR2 | |
| SCHEMBL26539683 | 0.89 | ESR1 (0.77) | ESR1 | |
| SCHEMBL19131430 | 0.89 | ESR1 (1.00) | ESR1ESR2AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037768-B1 | NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI SA (FR) | 2023-10-11 | — | — | EP | disclosed |