Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698268 | 0.81 | CYP1A2 (0.42) | CYP1A2KMT2ACYP2C19HIF1ACYP2D6 | |
| SCHEMBL1926958 | 0.81 | CYP1A2 (0.42) | CYP1A2KMT2ACYP2C19HIF1ACYP2D6 | |
| SCHEMBL26985796 | 0.78 | KCNN4 (0.56) | CYP1A2KMT2AMEN1CYP2C19HIF1A | |
| SCHEMBL1926065 | 0.78 | CYP2C19 (0.41) | CYP1A2KMT2ACYP2C19HIF1ACYP2D6 | |
| SCHEMBL8332082 | 0.77 | CYP1A2 (0.42) | CYP1A2KMT2AMEN1CYP2D6MAPT | |
| SCHEMBL1455681 | 0.76 | PIN1 (0.50) | CYP1A2KMT2AMEN1CYP2D6MAPT | |
| SCHEMBL7077556 | 0.76 | CYP2C19 (0.42) | CYP1A2KMT2AMEN1CYP2C19HIF1A | |
| SCHEMBL1624876 | 0.75 | CYP2C19 (0.44) | CYP1A2KMT2ACYP2C19HIF1ACYP2D6 | |
| Hydrochloric Acid SCHEMBL1977471 | 0.75 | PIN1 (0.49) | CYP1A2KMT2AMEN1CYP2D6MAPT | |
| SCHEMBL27579784 | 0.75 | KMT2A (0.46) | CYP1A2KMT2AMEN1CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| EP-2509941-A2 | N-ACYLATED HYDROXYLAMINE DERIVATIVES AND O-ACYLATED HYDROXYLAMINE DERIVATIVES | The Johns Hopkins University (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071951-A2 | N-ACYLOXYSULFONAMIDE AND N-HYDROXY-N-ACYLSULFONAMIDE DERIVATIVES | JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |