Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20942567 | 0.84 | USP2 (0.79) | BRD4USP2POLBKMT2ARAB9A | |
| SCHEMBL20942498 | 0.79 | POLB (0.82) | BRD4L3MBTL1USP2MAOBPOLB | |
| SCHEMBL20942525 | 0.79 | USP2 (0.65) | BRD4L3MBTL1USP2POLBMEN1 | |
| SCHEMBL19276665 | 0.79 | SMN1; SMN2 (0.63) | BRD4L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL20942542 | 0.77 | TAF1 (0.65) | BRD4RAB9ALMNAMAPT | |
| SCHEMBL30402413 | 0.77 | TAF1 (0.65) | BRD4RAB9ALMNAMAPT | |
| SCHEMBL20942538 | 0.77 | NPC1 (0.60) | BRD4USP2MEN1KMT2ARAB9A | |
| SCHEMBL20942539 | 0.77 | BRD4 (0.60) | BRD4L3MBTL1USP2MAOBPOLB | |
| SCHEMBL20942547 | 0.76 | BRD4 (0.67) | BRD4L3MBTL1USP2POLBRAB9A | |
| SCHEMBL20942536 | 0.76 | TAF1 (0.60) | BRD4RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017140728-A1 | TAF1 INHIBITORS FOR THE THERAPY OF CANCER | CEMM - FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GMBH (AT) | 2017-08-24 | — | — | WO | disclosed |